Therapy effect of melatonin and hypothermia on hypoxic-ischemic brain damage / 国际儿科学杂志
International Journal of Pediatrics
; (6): 105-107, 2011.
Article
in Zh
| WPRIM
| ID: wpr-401593
Responsible library:
WPRO
ABSTRACT
Melatonin has neuroprotective effect on hypoxic-ischemic brain damage(HIBD), which easily crosses the blood-brain barrier and plays neuroprotective role in reducing oxidative damage. Melatonin may be effective in preventing learing diabilities. It has been suggested that melatonin soporific effect is secondary to its ability to induce hypothermia. Neuroprotective effect of hypothmia has been proved. Howere, it is clear that hypothemia will not provide complete protection of HIBD and melatonin might augment protection of hypothemia in HIBD.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
International Journal of Pediatrics
Year:
2011
Document type:
Article