Isolation and Complete Nucleotide Sequence of the Measles Virus IMB-1 Strain in China / 中国病毒学·英文版
Virologica Sinica
; (6): 381-389, 2010.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-402284
Responsible library:
WPRO
ABSTRACT
The complete nucleotide sequence of the measles virus strain IMB-1, which was isolated in China, was determined. As in other measles viruses, its genome is 15,894 nucleotides in length and encodes six proteins. The full-length nucleotide sequence of the IMB-1 isolate differed from vaccine strains (including wild-type Edmonston strain) by 4% -5% at the nucleotide sequence level. This isolate has amino acid variations over the full genome, including in the hemagglutinin and fusion genes. This report is the first to describe the full-length genome of a genotype H 1 strain and provide an overview of the diversity of genetic characteristics of a circulating measles virus.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Virologica Sinica
Year:
2010
Document type:
Article