Function study of acid-sensing ion channels in non-neuronal tissues / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 147-150, 2010.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-404037
Responsible library:
WPRO
ABSTRACT
Acid-sensing ion channels(ASICs) are a novel class of ligand-gated cation channels activated by extracellular acidification and belong to the epithelial sodium channels(DEG/ENaC) superfamily.Their biological functions have recently been found not only in the central nervous system but also relevant to the physiology and pathology of non-neuronal tissues such as taste buds, cardiovascular system and bones.This review concerns the latest research on the expression and functions of ASICs in non-neuronal tissues so as to promote the understanding of their physiological and pathological functions.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2010
Document type:
Article