Sugammadex: clinical development and practical use / 대한마취과학회지
Korean Journal of Anesthesiology
; : 495-500, 2013.
Article
in En
| WPRIM
| ID: wpr-40684
Responsible library:
WPRO
ABSTRACT
Sugammadex is belonging to a new class of drugs: the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants. The mains advantages of sugammadex when compared with conventional anticholinesterase agents are a much faster recovery time and the unique ability, for the first time, to reverse rapidly and efficiently deep levels of neuromuscular blockade. However it only works for reversal of rocuronium or vecuronium-induced neuromuscular blockade. When administered 3 min after rocuronium the use of a large dose (16 mg/kg) can even reverse rocuronium significantly faster than the spontaneous recovery after succinylcholine.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Paralysis
/
Succinylcholine
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Cholinesterase Inhibitors
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Neuromuscular Blockade
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Cyclodextrins
/
Neostigmine
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Neuromuscular Depolarizing Agents
Language:
En
Journal:
Korean Journal of Anesthesiology
Year:
2013
Document type:
Article