Adolescent idiopathic scoliosis and melatonin: a survey on scoliosis in 8 198 adolescents from over 10 middle and primary schools in Haikou City / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
; (53): 202-203, 2005.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-407784
Responsible library:
WPRO
ABSTRACT
BACKGROUD It is not consistent on whether melatonin correlates with the adolescent idiopathic scoliosis(AIS) demonstrated by the domestic and foreign scholars.OBJECTIVE:
To study the pathogenesis of AIS and its correlation with melatonin.DESIGN:
A nonrandomized age-matched controlled study screened with two tests.SETTING:
The Second Department of Orthopaedics, Haikou People' s Hospital.PARTICIPANTS:
The experiment was completed in the Second Department of Orthopaedics, Haikou People' s Hospital. Totally 8 198 in-school students.from over 10 schools of towns in Haifu District, 4 423 males and 3 775 females, aged 7 to 16 years were surveyed.METHODS:
Forty-two adolescents who have been diagnosed with AIS were selected and 50 healthy age-matched adolescents were selected as controls. Melatonin was assayed with the radioimmunology and the data were processed statistically.MAIN OUTCOMEMEASURES:
The levels of serum melatonin in the two groups.RESULTS:
The serum melatonin of the preadolescents below 10 years old in AIS group, especially of females, was less than that of adolescents in the control group, with significant differencein statistics.CONCLUSION:
The serum melatonin correlates with pathogenesis of AIS.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2005
Document type:
Article