Domestic vs imported vecuronium bromide on effects of muscular relaxation / 中国新药与临床杂志

ABSTRACT

AIM: To compare domestic and imported vecuronium bromide on the effects of muscular relaxation and cardiovascular system.　METHODS: Thirty patients undergoing elective surgery were divided into domestic one group and exotic one group. The onset time, T1 recovery to 10% of control, clinical duration, T1 recovery to 75% of control and recovery index of each group were measured by train-of-four stimulation and recorded. The changes of arterial pressure and heart rate of each group were recorded before induction, before intubation, intubation, and 1,2,5 min after intubation.　RESULTS: The changes of arterial pressure and heart rate were not obvious diffecance between two groups. The effect of muscular relaxation did not differ after administration either.　CONCLUSION: The significant different changes between domestic and imported vecuronium bromide are not noticed. Both on the effects of muscular relaxation and cardiovascular system are similar.