Wnt signaling pathway antagonist SOX17 in cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 735-737, 2012.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-419448
Responsible library:
WPRO
ABSTRACT
SOX17,a member of the SOX family of transcription factors,is conserved in many species and plays an important role in the formation of embryo endoderm.A number of studies have found that SOX17 gene expression is silenced or decreased might be due to promoter bypermethylation,which plays a vital role in tumorigenesis and tumor progression,and may contribute to aberrant activation of canonical Wnt signaling pathway in several human malignant tumors.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2012
Document type:
Article