Correlation between the 95th nucleotide polymorphism of aldose reductase (AR) gene intron 8 and type 2 diabetic nephropathy / 中国糖尿病杂志

ABSTRACT

The study on aldose reductase gene intron 8 A95 C polymorphismin 209 type 2 dia-betic patients and 84 healthy controls showed that the frequency of genotype AAis 7 %in DN,higherthan that in non-nephropathy (1 %) and control (1 %) ,suggsting that intron 8 genotype AA may be arisk factor for diabetic nephropathy .