Clinical study of hyperbaric oxygen combining conventional therapy on traumatic brain injury with persistent vegetative state / 中国综合临床
Clinical Medicine of China
; (12): 639-641, 2012.
Article
in Zh
| WPRIM
| ID: wpr-425794
Responsible library:
WPRO
ABSTRACT
Objective To investigate the efficacy and mechanism of hyperbaric oxygen combining conventional therapy on persistent vegetative state ( PVS).Methods Sixty-two cases of PVS patients were treated with hyperbaric oxygen ( HBO ) combinting with conventional therapy.( 1 ) Hyperbaric oxygen therapy:hyperbaric oxygen chamber was adopted and the air pressure was 0,18 -0.20 MPa.The patients breathed pure oxygen for 30 min,2 times per day with a 10 min interval,and continued for 10 days as a course with an average of 4 to 6 courses.(2)Conventional therapy:All patients received drug treatment in hyperbaric oxygen therapy at the same time,including hemostasis,dehydration,anti-infection,nerve cell nutrition agents,wake promoting agents and supportive therapy.All patients were divided to three groups according to the course of disease:26 - 59 days in A group,60-119 days in B group,120 -268 days in C group,and the relationship between disease course and HBO treatment efficacy was analyzed.Results Afer HBO combining conventional therapy,27 cases (43.5%) were recovered,18 cases(29.0% ) had obvious effect,8 cases( 12.9% ) had effect,9 cases( 14.5% )were inefficacy.The efficiency related to the course of disease.The total efficiency rate was 85.5%.The efficacy of HBO treatment had significant difference in A,B and C group ( 96.2%,62.5% and 41.7% in A,B and C group respectively,x2 =24.83,P < 0.01 ).The shorter course indicated the better efficacy.Conclusion Hyperbaric oxygen combining conven.
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Database:
WPRIM
Language:
Zh
Journal:
Clinical Medicine of China
Year:
2012
Document type:
Article