Sex hormone replacement in Turner syndrome / 国际儿科学杂志

ABSTRACT

The cardinal features of Turner syndrome(TS) are short stature,congenital abnormalities,gonadal dysgenesis.The sex hormone insufficiency lead to infertility and lack of proper development of secondary sex characteristics,it also involves in the frequent osteoporosis and increased cardiovascular risk,state of physical fitness,insulin resistance,body composition,and may play a role in the increased incidence of autoimmunity.Recent researches emphasize the TS patients need for proper sex hormone replacement therapy to improve their quality of life.This review summarizes the effects of estrogen and androgen insufficiency as well as the effects of sex hormone replacement therapy on the whole body of Turner syndrome.