Experimental technology and methods of lymphatic metastasis in gastric cancer / 国际肿瘤学杂志

ABSTRACT

With the development of imaging technique and molecular biological technique,researchers all over the world have made a great many of studies on the mechanism and treatment of lymphatic metastasis.The discovery of lymphatic endothelial cell-specific markers make it clear to distinguish lymphatic endotheliocyte.The application of new techniques such as immunohistochemical method and reverse transcription polymerase chain reaction (RT-PCR) can study the lymphatic metastasis from the genetic and molecular level.The application of molecular imaging and nanoparticles could provide new detection methods and therapies.The establishment of animal models offers a solid foundation for experimental study.