Correlation between serum macrophage migration inhibitory factor and regulated on activation normal T cell expressed and secreted cytokines in patients with chronic hepatitis B / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
; (36): 1-3, 2013.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-432846
Responsible library:
WPRO
ABSTRACT
Objective To investigate the serum levels and correlation between macrophage migration inhibitory factor (MIF) and regulated on activation normal T cell expressed and secreted cytokines (RANTES) in patients with chronic hepatitis B (CHB).Methods Forty-four CHB patients (CHB group)and 30 healthy controls (control group) were enrolled in this study.The venous blood was collected and serum MIF and RANTES levels were detected by enzyme-linked immunosorbent assay.Correlation between MIF and RANTES was analyzed in CHB group.Results The serum MIF and RANTES levels in CHB group were significantly higher than those in control group [(8.48 ± 1.70) μ g/L vs.(1.99 ± 2.38) μ g/L,(3.94 ±2.38) μ g/L vs.(0.33 ± 0.15) μ g/L,P =0.000].There was no correlation between MIF level and RANTES level(r =0.212,P> 0.05).Conclusions The serum MIF and RANTES levels are significantly increased in patients with CHB,but there is no correlation.The participation pathogenesis way of CHB is different.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Postgraduates of Medicine
Year:
2013
Document type:
Article