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Long noncoding RNA in digestive system neoplasms / 中国肿瘤临床
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-435654
Responsible library: WPRO
ABSTRACT
Long noncoding RNA (lncRNA) comprises a group of RNAs that are longer than 200 nucleotides. The lncRNA does not contain functional open reading frames and cannot encode proteins. RNA accounts for a large proportion in the total noncoding RNAs. The number, type, and function of lncRNA are unclear, so they have been called the dark matter of the genome. With the applica-tion of a new generation of gene sequencing technology, lncRNA is found to be involved in the mechanisms mediating the signal trans-duction pathway, regulating the cell cycle, and inducing cell apoptosis. In this article, the authors summarized the up-to-date research progress on lncRNA in digestive system neoplasms in China and overseas to provide new insights into the genetic diagnosis and treat-ment of digestive system neoplasms in clinics.

Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Clinical Oncology Year: 2013 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Clinical Oncology Year: 2013 Document type: Article
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