MLL2 gene and tumor / 国际肿瘤学杂志
Journal of International Oncology
; (12): 569-571, 2013.
Article
in Zh
| WPRIM
| ID: wpr-437174
Responsible library:
WPRO
ABSTRACT
Histone methyltransferase modulates heterochromatin formation,genomic imprinting and genetic transcription by regulating the combination of histones and DNA.As encoding genes of histone methyltransferase,mixed-lineage leukemia (MLL) genes are found to have close relationship with tumors.Recently,MLL2,a member of this family,has been found highly expressed anomalously in breast cancer,colorectal cancer and lymphoma.Whether MLL2 participates in the progression of cancer,the time phase of its participation and its specific role are still remained to further study.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of International Oncology
Year:
2013
Document type:
Article