Blood flow simulation of internal carotid artery aneurysm using two-way flow-solid coupling method / 中国组织工程研究

ABSTRACT

BACKGROUND:The hemodynamics changes of aneurysm provide the basis for aneurysm treatment and ruptured aneurysm prevention, while finite element analysis is a good technical means. OBJECTIVE:To construct the two-way flow-solid coupling model of internal carotid artery aneurysm, and thus simulate its flows. METHODS:CT angiography data of internal carotid artery aneurysm were recorded with GE Lightspeed 64 spiral CT scanning, and the corresponding three-dimension model was constructed with mimics10.01 software. Then the fluid-solid coupled flow simulations were done depending on Ansys+Fluent software. RESULTS AND CONCLUSION:The two-way flow-solid coupling model of internal carotid artery aneurysm was built, with the same morphology and anatomy as the three-dimensional CT imaging. In the whole cardiac cycle, the blood flow of aneurysm body was swirl typed and its velocity was slower than that of the aneurysm neck;the deformation, wal shear stress, pressure and von Mises stress of aneurysm wal were the maximum at the neck, and the minimum at the top. Their highest value was at the 0.16 s (rapid ejection period), and their lowest value at the 0.74 s (relaxation period). On the basis of CT angiography data, to construct the two-way flow-solid coupling model of internal carotid artery aneurysm is a simple and practical method. The blood flow simulation of aneurysm is close to the human physiological conditions, and the results wil provide new theoretical basis for the study on the occurrence and development of aneurysm.