Caveolin-1 and cerebrovascular disease / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 75-78, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-444667
Responsible library:
WPRO
ABSTRACT
Caveolae are cholesterol-rich pits on the surface of cell membrane,and participate in various physiological processes.Caveolin-1 is an important membrane protein constituting caveolae.It exerts biological effects through binding a variety of signaling proteins.In the pathophysiological processes of cerebrovascular disease,caveolin-1 participates in maintaining the integrity of blood-brain barrier and stability of atherosclerotic plaques,and has regulating the release of inflammatory mediators and neuroprotection.This article reviews the associated advances in research on the correlation between caveolin-1 and cerebrovascular disease in order to provide a new idea for clinical therapy.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2014
Document type:
Article