Biological role of microRNAs in gastric cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 131-133, 2014.
Article
in Zh
| WPRIM
| ID: wpr-445248
Responsible library:
WPRO
ABSTRACT
MicroRNAs (miRNA) are a class of small non-coding RNA molecules that are rich in content and are highly con-served. miRNA can regulate vital biological processes, including cell division, differentiation, and cell apoptosis. Their expression is dysregulated in many diseases. miRNA are essential in the initiation and development of various cancers. Recent miRNA studies have gradually moved from basic molecular studies of cancer onto areas of clinical application. The use of miRNA as biomarkers for cancer diagnosis and target molecules for cancer treatment is increasingly being identified. This review summarizes the potential applications of miRNA as biomarkers for diagnosis and prognosis of gastric cancer, drug response, and susceptibility prediction.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Clinical Oncology
Year:
2014
Document type:
Article