Effect of assisted thoracic small incision on serum CK19 mRNA and Lunx mRNA in patients with lung cancer / 中国基层医药

ABSTRACT

Objective To study the effect of assisted thoracic small incision on serum CK19 mRNA and Lunx mRNA in patients with lung cancer.Methods 90 patients with lung cancer were randomly divided into the control group and the observation group.45 patients in the control group were operated through thoracotomy,while 45patients in the observation group were operated through assisted thoracic small incision.Serum CK19 mRNA and Lunx mRNA were detected before and after operation through RT-PCR.Results Serum CK19 mRNA and Lunx mRNA were decreased after operation (t =19.682,12.784,7.824,7.085,all P ＜ 0.01).And the mRNA levels in the observation group were lower than those in the control group (t =1.900,1.438,all P ＜ 0.05).Conclusion Assisted thoracic small incision can decrease serum CK19 mRNA and Lunx mRNA in patients with lung cancer,which can improve micrometastasis.