Recurrent Acute Pericarditis Induced by 5-aminosalicylates in a Patient with Inflammatory Bowel Disease
Intestinal Research
; : 289-294, 2012.
Article
in Ko
| WPRIM
| ID: wpr-45082
Responsible library:
WPRO
ABSTRACT
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammation of the intestines. IBD treatment may require anti-inflammatory agents such as sulfasalazine or 5-aminosalicylate (5-ASA) and immunomodulators to control the symptoms. However, these agents have a variety of common adverse effects such as nausea, vomiting, skin rash, leukopenia, thrombocytopenia, and infections. Moreover, rare side effects such as nephrotic syndrome, pneumonitis, and pericarditis can occur. A 21-year-old male was admitted to the hospital due to acute chest pain, fever, and sweating. The patient had a history of Crohn's disease and had been taking mesalazine for 3 weeks. Chest x-ray, echocardiography, and clinical manifestations revealed that the patient had acute pericarditis. However, we did not recognize the relationship between these findings and 5-ASA at that time. Two years later, the patient took 5-ASA again, and similar symptoms occurred, which led us to confirm that he suffered from pericarditis induced by this drug. We report a case of acute recurrent pericarditis that developed after taking 5-ASA for IBD treatment with a review of the literature.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pericarditis
/
Pneumonia
/
Sulfasalazine
/
Sweat
/
Sweating
/
Thorax
/
Thrombocytopenia
/
Vomiting
/
Chest Pain
/
Echocardiography
Limits:
Humans
/
Male
Language:
Ko
Journal:
Intestinal Research
Year:
2012
Document type:
Article