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Recurrent Acute Pericarditis Induced by 5-aminosalicylates in a Patient with Inflammatory Bowel Disease
Intestinal Research ; : 289-294, 2012.
Article in Ko | WPRIM | ID: wpr-45082
Responsible library: WPRO
ABSTRACT
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammation of the intestines. IBD treatment may require anti-inflammatory agents such as sulfasalazine or 5-aminosalicylate (5-ASA) and immunomodulators to control the symptoms. However, these agents have a variety of common adverse effects such as nausea, vomiting, skin rash, leukopenia, thrombocytopenia, and infections. Moreover, rare side effects such as nephrotic syndrome, pneumonitis, and pericarditis can occur. A 21-year-old male was admitted to the hospital due to acute chest pain, fever, and sweating. The patient had a history of Crohn's disease and had been taking mesalazine for 3 weeks. Chest x-ray, echocardiography, and clinical manifestations revealed that the patient had acute pericarditis. However, we did not recognize the relationship between these findings and 5-ASA at that time. Two years later, the patient took 5-ASA again, and similar symptoms occurred, which led us to confirm that he suffered from pericarditis induced by this drug. We report a case of acute recurrent pericarditis that developed after taking 5-ASA for IBD treatment with a review of the literature.
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Full text: 1 Database: WPRIM Main subject: Pericarditis / Pneumonia / Sulfasalazine / Sweat / Sweating / Thorax / Thrombocytopenia / Vomiting / Chest Pain / Echocardiography Limits: Humans / Male Language: Ko Journal: Intestinal Research Year: 2012 Document type: Article
Full text: 1 Database: WPRIM Main subject: Pericarditis / Pneumonia / Sulfasalazine / Sweat / Sweating / Thorax / Thrombocytopenia / Vomiting / Chest Pain / Echocardiography Limits: Humans / Male Language: Ko Journal: Intestinal Research Year: 2012 Document type: Article