A matched case-control study of risk factors in abdominal aortic aneurysm / 北京大学学报(医学版)
Journal of Peking University(Health Sciences)
; (6): 412-416, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-452052
Responsible library:
WPRO
ABSTRACT
Objective:
To examine the potential influence factors of abdominal aortic aneurysm (AAA).Methods:
A 1∶2 pair-matched, case-control study was conducted from July 2011 to December 2012 .A pair was composed of one AAA patient recruited from the Vascular Surgery Department , Chinese PLA General Hospital and two gender-and age-matched non-AAA subjects , one from the same hospital and the other from the community in Fangshan District in Beijing .Demographic data , medical history and the lifestyle of each subject were collected .Moreover , all the participants underwent abdominal ultra-sound or computed tomography ( CT ) and peripheral venous blood samples were obtained .Results:
There were 155 case/control pairs .The multivariate conditional logistic regression model confirmed that suffering from hypertension conferred a 1.98-fold (95%CI 1.12-3.18) increased likelihood of AAA. Smoking was a strong independent risk factor of AAA , with odds ratios ( 95% confidence intervals ) of 5.23 (2.44-11.23).Dyslipidemia(OR=2.61,95%CI 1.45-4.70), a higher level of serum hs-CRP (OR=2.43,95%CI 1.37-4.31) and homocysteine (OR=2.73,95%CI 1.61-4.65) were all asso-ciated with AAA.Conclusion:
Hypertension and smoking are the risk factors of AAA .Dyslipidemia, hsCRP and Hcy are associated with AAA .
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Journal of Peking University(Health Sciences)
Year:
2014
Document type:
Article