Role of the AhR ligand in the development of tumor / 中国生化药物杂志

ABSTRACT

Aryl hydrocarbon receptor (AhR) is a ligand-dependent activation of transcription factor, which is activated by a large variety of ligands, resulting in the expression of metabolic enzymes and a series of downstream gene activation, and closely related with tumor development . Now a review for AhR ligands with different structural and functional and its relationship with tumor, in order to provide a new target for tumor therapy.