C-Kit-Negative Gastrointestinal Stromal Tumor in the Stomach
Journal of Gastric Cancer
; : 290-294, 2015.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-45379
Responsible library:
WPRO
ABSTRACT
C-kit-negative gastrointestinal stromal tumors (GISTs) are uncommon, and there have been few reports about the diagnosis and treatment of c-kit-negative GISTs in the stomach. We report the case of a patient who was diagnosed with a huge and atypical GIST in the stomach. The GIST was completely resected and finally diagnosed as c-kit-negative GIST based on immunohistochemical staining of tumor cells, which were negative for CD117 and CD34 and positive for Discovered on GIST-1 (DOG1). C-kit-negative GISTs could be treated by complete resection and/or imatinib, which is the same treatment for c-kit-positive GISTs.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Proto-Oncogene Proteins c-kit
/
Gastrointestinal Stromal Tumors
/
Diagnosis
/
Imatinib Mesylate
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Journal of Gastric Cancer
Year:
2015
Document type:
Article