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Pulmonary Calciphylaxis Associated with Acute Respiratory and Renal Failure Due to Cryptogenic Hypercalcemia: An Autopsy Case Report
Article in English | WPRIM (Western Pacific) | ID: wpr-45633
Responsible library: WPRO
ABSTRACT
Metastatic calcification is rare; it is found during autopsy in patients who underwent hemodialysis. Diffuse calcium precipitation of small and medium-sized cutaneous vessels, known as calciphylaxis, can result in progressive tissue necrosis secondary to vascular calcification. This condition most commonly involves the skin; however, a rare occurrence of visceral calciphylaxis has been reported. Here we report on an autopsy case. Despite a thorough evaluation, and even performing an autopsy, the underlying cause of acute-onset hypercalcemia, resulting in the production of pulmonary calciphylaxis and metastatic renal calcification associated with acute respiratory and renal failure, could not be determined. Metastatic calcification often lacks specific symptoms, and the degree of calcification is a marker of the severity and chronicity of the disease. This unusual autopsy case emphasizes the importance of rapidly progressing visceral calciphylaxis, as well as its early detection.
Subject(s)

Full text: Available Database: WPRIM (Western Pacific) Main subject: Autopsy / Calciphylaxis / Calcium / Renal Dialysis / Renal Insufficiency / Vascular Calcification / Hypercalcemia / Necrosis Type of study: Screening study Limits: Humans Language: English Journal: Korean Journal of Pathology Year: 2012 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Main subject: Autopsy / Calciphylaxis / Calcium / Renal Dialysis / Renal Insufficiency / Vascular Calcification / Hypercalcemia / Necrosis Type of study: Screening study Limits: Humans Language: English Journal: Korean Journal of Pathology Year: 2012 Document type: Article
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