Regulation and significance of acidification of plasma membrane and intracellular membranes / 医学研究生学报
Journal of Medical Postgraduates
; (12): 1223-1225, 2014.
Article
in Zh
| WPRIM
| ID: wpr-458372
Responsible library:
WPRO
ABSTRACT
Acidic environment of organelles of eukaryotic cells plays an important role in endocytosis, the secretion of lysoso-mal enzymes and other physiological activities.V-ATPase (vacuolar ATPases) and CLC (chloride channel) family are widely distribu-ted and present in virtually all eukaryotic cells in intracellular membranes and in the plasma membrane.They are responsible for the a-cidification of the vesicular interior.In this paper, the distribution, structure, mechanism of action and physiological and pathological significance of V-ATPase and CLC protein are discussed.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of Medical Postgraduates
Year:
2014
Document type:
Article