The effect of artemisinin on the proliferation of human hepatoma cell line HepG-2 / 重庆医学
Chongqing Medicine
; (36): 21-23, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-462806
Responsible library:
WPRO
ABSTRACT
Objective To investigate the effect of artemisinin on the proliferation of human hepatoma cell line HepG‐2 .Methods The inhibition effect of cell proliferation in human hepatocelluar carcinoma cell line HepG2 of artemisinin was detected by MTT test ,and the cell cycle and apoptosis were detected by Flow cytometry .Results Artemisinin at 80 umol/L could effectively inhibi‐ted the proliferation of HepG‐2 cell in a dose‐and time‐dependent manner;the drugs could block cells at G0/S phase ,and induct the HepG‐2 cell apoptosis .Conclusion Artemisinin could effectively inhibit the proliferation of HepG‐2 cell .
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chongqing Medicine
Year:
2015
Document type:
Article