The value of serum albumin level for the prognosis of late-preterm infants infection / 中国新生儿科杂志
Chinese Journal of Neonatology
; (6): 196-199, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-464022
Responsible library:
WPRO
ABSTRACT
Objective To study the value of serum albumin ( ALB ) level for the prognosis of late-preterm infants infection. Methods Late-preterm infants admitted to the neonatal intensive care unit ( NICU) from July 2012 to July 2013 were recruited and their clinical data retrospectively reviewed, including the laboratory examination results, neonatal critical illness scores ( NCIS ) , perinatal complications and prognosis. The infants were assigned into three groups based on ALB levels (>30 g/L, 25-30 g/L, <25 g/L). Results A total of 257 cases were recruited and 122 cases (47. 4%) had ALB levels <25 g/L. 32 had neonatal sepsis ( sepsis group) , 190 neonatal infection ( infection group) and 35 without infection ( no-infection group ) . The incidences of hypoalbuminemia among these groups were 84. 4%, 50. 0% and 28. 6%, with the mortality rate 15. 6%, 0. 5% and 0%. The incidence of hypoalbuminemia and mortality rate in sepsis group were significantly higher than the other groups ( P<0. 05 ) , and no statistically significant differences between infection group and no-infection group ( P<0. 05). The ALB level in survived infants [(29. 6±7. 5)g/L] was statistically higher than the deceased ones [(20. 4±6. 9)g/L](P<0. 05). The incidence of critically ill newborns was 65. 5% in ALB <25 g/L group, significantly higher than the other groups (P<0. 05). 26. 2% in ALB <25 g/L group had more than 4 organs injuries, significantly higher than ALB >30 g/L group ( P<0. 05 ) . Conclusions Hypoalbuminemia is common among neonates with sepsis. The ALB level had predictive value for the prognosis of neonatal infection.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Neonatology
Year:
2015
Document type:
Article