Research progress of MEG3 long noncoding RNA / 国际肿瘤学杂志
Journal of International Oncology
; (12): 118-121, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-466621
Responsible library:
WPRO
ABSTRACT
Maternally expressed gene 3 (MEG3) is a tumor-suppressing gene,and MEG3 RNAs,its products,are a series of long noncoding RNAs.The MEG3 gene is lost in kinds of human tumors,further more,the methylation of related DNA region is directly associated with the deficiency of MEG3 expression.Studies show that MEG3 gene and MEG3 RNAs can inhibit cell proliferation and induce apoptosis,which is associated with the fuction of tumor suppressor gene p53.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2015
Document type:
Article