Diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms / 中华消化外科杂志
Chinese Journal of Digestive Surgery
; (12): 756-759, 2014.
Article
in Zh
| WPRIM
| ID: wpr-466917
Responsible library:
WPRO
ABSTRACT
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are exceedingly rare tumor,with an increasing incidence in recent years.According to the NANETS consensus guidelines for the diagnosis of neuroendocrine tumor,the algorithm for diagnosis of GEP-NENs includes clinical syndrome suggestive of NENs,biochemical testing,genetic testing,tumor localization by imaging and tissue diagnosis.GEP-NENs could be divided into functional versus non-functional based on the clinical manifestations.Radical surgery is the standard firstline therapy for limited-stage tumors.However,two-thirds of GEP-NENs patients are inoperable for tumor metastasis at initial diagnosis.For these advance staged patients,multidisciplinary treatment is the best choice,which includes surgery,chemotherapy,biotherapy,molecular targeted therapy,somatostatin receptor-targeted radionuclide therapy.Molecular targeted therapy may turn into a standard first-line therapy for its good curative effect in recent studies.
Full text:
1
Database:
WPRIM
Type of study:
Diagnostic_studies
/
Guideline
Language:
Zh
Journal:
Chinese Journal of Digestive Surgery
Year:
2014
Document type:
Article