Hyperthermia Combined with Chemotherapy for Ovarian Cancer:A Meta-analysis / 中国医科大学学报
Journal of China Medical University
; (12): 489-493, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-468213
Responsible library:
WPRO
ABSTRACT
Objective To assess the effectiveness and safety of hyperthermia combined with chemotherapy(HCT)compared with chemotherapy (CT)for ovarian cancer. Methods Related literatures were searched by two independent investigators from the following electronic databasesPubMed,Cochrane Library,EMbase,VIP,WanFang Data,CNKI and CBM.Then the meta?analysis was performed by using RevMan 5.3 software. Results A total of 10 RCTs involving 546 patients were included. The results of Meta?analysis showed that the HCT group was superior to the CT group in the effective rate,tumor control rate,effective rate of CA125,ascites control rate and PD,with significant differences(P0.05). Conclusion Compared with CT,HCT can significantly increase short?term curative effect,ameliorate the quality of life,and it does not increase the incidence of adverse reactions. HCT is worthy of clinical applica?tion.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Systematic review
Aspects:
Patient-preference
Language:
Chinese
Journal:
Journal of China Medical University
Year:
2015
Document type:
Article