Research progress of microRNA in the transformation from myelodysplastic syndromes into acute leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 569-572, 2014.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-474629
Responsible library:
WPRO
ABSTRACT
microRNA (miRNA) is a kind of 18 to 25 nucleotide non coding RNAs,which plays an important role in various ways.The abnormal miRNA expression patterns lead to many diseases of hematopoietic system.Myelodysplasitc syndromes (MDS) comprise a heterogeneous group of disorders characterized by ineffective hematopoiesis,bone marrow dysplasia and variable propensity of transformation to acute myeloid leukemia (AML).20 %-30 % MDS patients may progress to AML.miRNA plays a key role in the develpoment,advance and prognosis of MDS.In this paper,the related miRNAs in the transformation from MDS into AML were reviewed.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2014
Document type:
Article