Study on changes of blood cell distribution width and D-dimer in patients with chronic obstructive pulmonary disease / 中国生化药物杂志

ABSTRACT

Objective To investigate the changes of blood cell distribution width and D-dimer in patients with chronic obstructive pulmonary disease.Methods 60 cases with chronic obstructive pulmonary disease were selected and according to the course of disease were divided into two groups.30 healthy people were selected to be the control group.MCV, RDW and D-dimer were detected and compared.ResuIts Compared with the control group, MCV and RDW of acute phase group and remission stage group are higher(P<0.05), compared with the remission stage group, MCV and RDW of acute phase group were higher(P<0.05), and RDW and MCV in the acute stage group were positively correlated with the remission stage group (r=0.717, 0.902, P<0.05).Compared with the control group, D-dimer of acute phase group and remission stage group were higher(P<0.05), compared with the remission stage group, D-dimer of acute phase group were higher(P<0.05), and D-dimer in the acute stage group were positively correlated with the remission stage group (r=0.727, P<0.05).ConcIusion The distribution of blood cell distribution width and D-dimer levels in patients with chronic obstructive pulmonary disease in acute stage and remission stage group were increased, and the increasing of patients with chronic obstructive pulmonary disease in the acute stage is more obvious.