Microfluidic chip digital PCR technology and its clinical application / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
; (12): 592-594, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-479296
Responsible library:
WPRO
ABSTRACT
Microfluidics-based digital PCR depends on microfluidic chip to split PCR reaction mixture into many tiny equal-volume units.Quantitative assessment of target DNA template can be obtained by counting the number of fluorescence-positive units after thermocycling.Microfluidics-based digital PCR exhibits many advantages including absolute quantification, high sensitivity and accuracy, and shows great promise in a variety of applications, such as infectious diseases diagnose, early cancer detection and prenatal diagnose. There are already several microfludics-based digital PCR products produced from sereval companies.It is believed that as the technology improves, microfluidics-based digital PCR will find broader applications and become the next-generation tool for genetic tests.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Chinese Journal of Laboratory Medicine
Year:
2015
Document type:
Article