Influential factors and nursing measures for mental disorders after liver transplantation / 现代临床护理

ABSTRACT

Objective To investigate the influential factors and nursing measures for mental disorders after liver transplantation. Methods Seventy-two patients had undergone liver transplantation and thirty-eight of them affected mental disorders and 34 of them did not. The mental disorder group and the non-mental disorder group were compared in terms of sex, age, mechanical ventilation time, pressure percentage mean of arterial pressure, intraoperative blood loss, duration of operation time, ICU stay time, postoperative pain duration and degree, Bullock complex (tacrolimus, FK506) blood drug concentration, history of preoperative hepatic encephalopathy, postoperative use of sedatives, postoperative constraint, postoperative metabolic abnormalities and disorders and infection. The plain logistic regression analysis was used to abstract the risk factors for mental disorders. Results The independent influential factors for the complicated mental disorders included the mean arterial pressure lower than that of pressure percentage> 20%, postoperative pain duration > 5 h and score by the numerical rating scale ( NRS ) > 4 , FK506 blood drug concentration> 13 ng/mL, postoperative abnormality, disturbance of metabolism and infection (P < 0.01). Conclusion The incidence rate of postoperative mental disorders is high among the patients having undergone liver transplantation. The influential factors for the mental disorder include blood pressure and postoperative pain duration and degree , FK506 blood drug concentration and metabolic abnormalities and disorders, and infection. The nursing measures like family nursing, effective control of blood pressure, postoperative analgesia, monitoring the drug concentration, maintaining a stable environment and preventing infection after liver transplantation are critical for the reduced rate of mental disorder.