Analysis of the influence factors of cirrhosis complicated with upper gastrointestinal hemorrhage / 中国综合临床

ABSTRACT

Objective To explore the influence factors of cirrhosis complicated with upper gastrointestinal bleeding,and to guide the clinical treatment of patients with cirrhosis and prevent upper gastrointestinal bleeding.Methods One hundred and seventy-five cases patients with cirrhosis and upper gastrointestinal bleeding were treated in the Infectious Disease Hospital of Tangshan and the Affiliated Hospital of North China University of Science and Technology from July 2013 to July 2015 as the case group.One hundred and eighty-two patients with cirrhosis and no upper gastrointestinal bleeding at the same period in hospital as the control group.A face to face questionnaire was used to fill in the questionnaire.Results Multifactor conditional Logistic regression analysis showed that onset season (OR =4.185,95％ CI1.874-8.354),non steroidal drugs (OR =6.215,95％ CI2.681-15.532),drinking (OR =5.481,95％ CI3.205-11.225),portal vein highpressure gastropathy(OR =7.658,95％ CI3.227-14.714),diameter of portal vein (OR =8.901,95％ CI1.218-9.026),liver function classification (OR =13.124,95 ％ CI2.107-15.228) and esophageal varices (OR =11.021,95％ CI2.181-13.487) were related with patients with liver cirrhosis complicated with upper digestive tract hemorrhage.Conclusion The onset season,nonsteroidal anti-inflammatory drugs,drinking,portal hypertensive gastropathy,portal vein diameter,liver function classification and esophageal varices are the risk fators of liver cirrhosis complicated with upper digestive tract hemorrhage factors.