Meta-analysis of the level of adiponectin in chronic obstructive pulmonary disease / 中国综合临床
Clinical Medicine of China
; (12): 142-145, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-488508
Responsible library:
WPRO
ABSTRACT
Objective To investigate the clinical significance of the level of adiponectin (APN) in patients with chronic obstructive pulmonary disease(COPD).Methods The case-control study involving APN in OSAHS were searched and identified from Cochrane Library,PubMed,Embase,China Academic Journals Full-text database,VIP Database,and Full text database of China' s.According to inclusion and exclusion criteria,evaluated the quality of choice experiment,and then extracted the valid data for meta-analysis.Results Seven articles were selected,including 2 in SCI,5 in Chinese.Meta analysis showed that APN in acute exacerbation COPD group was significantly higher than in COPD group (standardized mean difference (SMD) =2.32,95%CI=0.62-4.02,P<0.05).Compared with normal control group,APN in COPD was higher (SMD=1.39,95%CI=1.00-1.78,P<0.01).Determined publication bias by Begg's and Egger's test,the results did not show any bias (P> 0.05).Conclusion The serum APN of COPD patients are significantly elevated,the APN testing in some extent reflect the severity of COPD.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Prognostic study
/
Systematic review
Language:
Chinese
Journal:
Clinical Medicine of China
Year:
2016
Document type:
Article