Clinical observation of Fufangqiaoruisu granule in the treatment of 76 children with bronchial asthma / 中国基层医药

ABSTRACT

Objective To study the clinical effect of Fufangqiaoruisu granule in the treatment of children with bronchial asthma.Methods 152 children with bronchial asthma were randomly divided into treatment group and control group.All the patients were treated with based therapy,and the patients in the control group were treated with montelukast,the patients in the treatment group received montelukast/Fufangqiaoruisu granule.The clinical symptoms such as cough,asthma were compared,and also the total effective rate.Results The disappear time of clinical symp-toms of cough,ashma,moist rale in the treatment group were (3.8 ±1.0) days,(3.5 ±0.8) days,and (2.1 ± 0.6)days,which were much shorter than (5.2 ±0.7)days,(4.7 ±0.9)days,(3.0 ±0.5)days in the control group, the differences were statistically significant(t =4.56,5.12,4.89,all P <0.05).After treatment,the FVC,FEV1 and PEF in the treatment group were (4.9 ±1.7)L,(3.8 ±0.6)L and (3.9 ±0.5)L/min,which in the control group were (3.2 ±1.2)L,(2.1 ±0.8)L and (2.8 ±0.5)L/min,(t =5.12,4.87,5.32,all P <0.05).The total effective rate of the observation group was 92.1%,which of the control group was 73.7%,the difference was statistically significant(χ2 =1.62,P =0.027).Conclusion Fufangqiaoruisu granule shows satisfactory clinical efficacy in the treatment of bronchial asthma,and it is worthy of clinical use.