Statistical Interpretation in Making DNA-based Identifications of Mass Victims / 대한법의학회지
Korean Journal of Legal Medicine
; : 55-60, 2008.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-49168
Responsible library:
WPRO
ABSTRACT
DNA profiles have been increasingly used as the most reliable means to identify remains from war or mass disaster. To establish the identity with such a large set of victims, special care should be taken to correlate remains with correct family references while avoiding coincidental match between non-relatives. Therefore we address here relevant statistical and combinatorial issues in the DNA identification of mass victims. A simple and general formula for the likelihood ratio governing any potential kinship between two DNA profiles was presented, and for that purpose, the probabilities that a given relative and an individual share autosomal identical-bydescent alleles were calculated. In addition, a method dealing with the allele drop-out in kinship analysis and the estimation of a cold hit were discussed.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
DNA
/
Cold Temperature
/
Disasters
/
Alleles
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Legal Medicine
Year:
2008
Document type:
Article