Roles of microRNAs in the anti-tumor effects of metformin / 国际肿瘤学杂志
Journal of International Oncology
; (12): 681-683, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-497403
Responsible library:
WPRO
ABSTRACT
Recent epidemiologic data indicate that metfomin has an anti-tumor effect.However,the underlying anti-tumor mechanisms remain unclear.MicroRNAs (miRNAs)can exhibit pro-oncogenic or anti-oncogenic effects by regulating the differentiation and proliferation of cells.In vitro studies show that metformin can regulate the expressions of multiple miRNAs which are closely associated with tumor development,a process possibly relating to the anti-cancer roles of metformin.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2016
Document type:
Article