Clinical Manifestations and Prognostic Factors of IgA Nephropathy with Long-Term Follow-Up / 대한내과학회지
Korean Journal of Medicine
; : 46-53, 2015.
Article
in Ko
| WPRIM
| ID: wpr-49744
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS: Immunoglobulin A nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide. Although several studies have identified IgAN prognostic factors in Korea, the follow-up period was insufficient to evaluate the natural history of IgAN. METHODS: A total of 471 patients were diagnosed with IgAN after percutaneous renal biopsy between April 1985 and March 2003. Patients with secondary IgAN and patients with a follow-up 1.3 mg/dL, estimated glomerular filtration rate or = 1 g/day, and severe renal pathology by the Haas sub-classification were significantly associated with ESRD. When these factors were included in multivariate Cox regression analyses, only severe renal pathology by the Haas sub-classification was an independent prognostic factor for IgAN. CONCLUSIONS: Careful follow-up and treatment is recommended, particularly in patients with IgAN and severe renal pathology by the Haas sub-classification.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pathology
/
Prognosis
/
Proteinuria
/
Biopsy
/
Serum Albumin
/
Survival Rate
/
Follow-Up Studies
/
Natural History
/
Creatinine
/
Diagnosis
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Medicine
Year:
2015
Document type:
Article