Drug reaction with eosinophilia and systemic symptom induced in a 9-year-old boy
Allergy, Asthma & Respiratory Disease
; : 296-300, 2016.
Article
in Ko
| WPRIM
| ID: wpr-49804
Responsible library:
WPRO
ABSTRACT
The drug reaction with eosinophilia and systemic symptom (DRESS) is a severe adverse drug-induced reaction. Acetaminophen is extensively used as an over-the-counter drug as well as a medical therapeutic. In spite of its frequent use, drug eruptions related to DRESS caused by acetaminophen are rare. This case report describes a 9-year-old boy who experienced fever and maculopapular skin rashes after taking acetaminophen. Leukocytosis with marked eosinophilia and slightly elevated levels of liver enzymes were observed. Symptoms resolved after withdrawal of acetaminophen, followed by intravenous methylprednisolone administration. The diagnosis of DRESS induced by acetaminophen was confirmed by an oral challenge test after 2 months. No allergic reactions to ibuprofen were observed.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Methylprednisolone
/
Ibuprofen
/
Drug Eruptions
/
Diagnosis
/
Drug Hypersensitivity
/
Eosinophilia
/
Exanthema
/
Fever
/
Hypersensitivity
/
Leukocytosis
Type of study:
Diagnostic_studies
Limits:
Child
/
Humans
/
Male
Language:
Ko
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2016
Document type:
Article