Research progress on focal adhesion kinase in malignant tumors / 实用肿瘤学杂志
Practical Oncology Journal
; (6): 162-166, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-499276
Responsible library:
WPRO
ABSTRACT
Focal adhesion kinase( FAK) ,a cytoplasmic non-receptor protein tyrosine kinase,serves as both a molecular scaffold and a mediator participating in multiple signal transduction pathways.FAK is involved in tumor cell survival,proliferation,migration and metastasis.Recent studies have shown that FAK is expressed in many tumor cells.Currently,FAK has been regarded as a potential target for cancer therapy.This review is to summarize the relationship between FAK and tumor progression.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Practical Oncology Journal
Year:
2016
Document type:
Article