Current status and recognition of pulmonary surfactant for the treatment of acute respiratory distress syndrome / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
; (24): 1372-1375, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-502127
Responsible library:
WPRO
ABSTRACT
Exogenous surfactant replacement has been successfully achieved and become standard therapy in neonatal respiratory distress syndrome,but clinical trials in acute respiratory distress syndrome (ARDS) had mixed results.Early studies show that pulmonary surfactant(PS) administration in ARDS can significantly improve oxygenation and decrease mortality,but in recent years,some clinical trials haven't achieve the most substantial benefits to long-term patient outcomes.The inconsistent results of clinical trials may have related to aspects of drug composition,dosing,delivery,and timing.At this time,surfactant therapy cannot be recommended as routine therapy in pediatric ARDS.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.2: Reduce avoidable death in newborns and children under 5
/
Other Respiratory Diseases
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2016
Document type:
Article