The factors affecting the survival and prognosis of patients with Ⅲ ~ Ⅳ gastric cancer: a report of 156 cases / 中国医师杂志
Journal of Chinese Physician
; (12): 1185-1189, 2016.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-502252
Responsible library:
WPRO
ABSTRACT
Objective To investigate the factors affecting the survival and prognosis of patients with stage Ⅲ~ Ⅳgastric cancers.Methods A total of 156 cases of Ⅲ ~ Ⅳ gastric cancer was studied retrospectively from September 1,2006 to December 31,2012.Kaplan-Meier analysis,Log-rank univariate analysis,Cox proportional hazards model analysis were used to analyze survival and prognostic factors.Results Twelve cases were lost,to the end of the follow-up,22 cases were alive.The median survival time was 29.3 months.1-year,3-year,and 5-year overall survival rates were 83.3%,37.8%,and 21.2%,respectively.Univariate analysis showed that tumor size,tumor node metastasis (TNM) staging,curative resection,hyperthermic intraperitoneal perfusion chemotherapy (HIPEC),and postoperative chemotherapy were correlated with prognosis (P <0.05 for all).Multivariate analysis showed that TNM staging,curative resection,HIPEC,and postoperative chemotherapy were independent prognostic factors (P < 0.01 for all).Conclusions TNM staging,curative resection,hyperthermic intraperitoneal perfusion chemotherapy and postoperative chemotherapy are the independent factors affecting the prognosis of stage Ⅲ~ Ⅳ gastric cancer after resection.Hyperthermic intraperitoneal perfusion chemotherapy and postoperative chemotherapy can improve their survival.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2016
Document type:
Article