Detection of CD35on Erythrocytes and Erythrocyte Chemokine Recepter(ECKR)in Patients with Psoriasis / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)1995.
Article
in Zh
| WPRIM
| ID: wpr-520415
Responsible library:
WPRO
ABSTRACT
Objective To study CD35on erythrocytes and erythrocyte chemokine recepter(ECKR)in patients with psoriasis in order to explore red blood cell(RBC)innate immune function and its possible role in the pathogenesis of psoriasis.Methods The rapid natural immune reaction on cancer cells was measured with RBCs isolated from fresh blood.Expression of CD35on erythrocytes was detected by flow cy-tometry.The level of IL-8,which was bound to isolated erythrocytes,was measured by enzyme linked im-munosorbent assay(ELISA)in the supernatant after centrifugation,which represented ECKR binding activity.Results Rosette formation rates of RBC adhering to cancer cells and expression of CD35on RBCs were significantly higher in psoriatic patients than those in control group(P
Full text:
1
Database:
WPRIM
Type of study:
Diagnostic_studies
Language:
Zh
Journal:
Chinese Journal of Dermatology
Year:
1995
Document type:
Article