Expression and role of CD134 and NF-?B in renal tissue of lupus nephritis / 中国病理生理杂志
Chinese Journal of Pathophysiology
; (12)1999.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-521330
Responsible library:
WPRO
ABSTRACT
AIM:
To investigate the role of CD134 (OX40) and NF-?B in the pathogenesis of lupus nephritis (LN).METHODS:
Renal in situ CD134 and NF-?B expression were examined in 40 biopsy specimens from LN patients by immunohistochemistry and microwave-based immunohistochemistry, respectively. The relationship between expression of CD134 and NF-?B was analyzed.RESULTS:
The expression of glomerular and tubular CD134 and NF-?B in LN were higher than that in normal control, especially in class Ⅳ LN, where there was intense staining of endothelial cell, distal tubules, and interstitial mononuclear cell. The CD134 expression of glomerular and tubular was closely related to NF-?B expression, respectively ( r=0.5542,P
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1999
Document type:
Article