Detection of Gene Mutations in a Family of Congenital Atrichia with Papular Lesions / 中华皮肤科杂志
Chinese Journal of Dermatology
; (12)2003.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-526023
Responsible library:
WPRO
ABSTRACT
Objective To detect gene mutations in a family of congenital atrichia with papular lesions (APL). Methods Polymerase chain reaction and DNA sequencing were used to search for mutations in the HR gene (a causative gene of APL), the CJB6 gene, and the CDSN gene. Results No mutation was found in these three genes except for single nucleotide polymorphisms (SNPs) in the HR and CDSN genes. Conclusion No mutation is identified in the HR, CJB6 or CDSN gene in this family affected by congenital APL.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Dermatology
Year:
2003
Document type:
Article