Study on Base Material Optimization of Oxaprozin Gel / 中国药房
China Pharmacy
; (12)2005.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-526048
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To observe the effects of different types of carbomers on percutaneous permeability of oxaprozin gels in vitro and to opitmize the formulation of oxaprozin gel.METHODS:
The permeability test in vitro was carried out by using Franz diffusion cell with rats' ex vivo skin as barrier.RESULTS:
The ex vivo permeability of oxaprozin gel was the best when the carbomer 940 used as its base material with its ex vivo permeability coefficient at 22.77?g/ (cm2?h) .CONCLUSION:
The optimized gel base material can act as bases for the production of oxaprozin gel.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Document type:
Article