The recombinant antibody HBsAg-Fab of hepatitis B virus to block hepatitis B reinfection after liver transplantation: a research in vitro / 中国普通外科杂志

ABSTRACT

Objective To study the effect of recombinant antibody HBsAg-Fab of hepatitis B virus(HBV) to block hepatitis B reinfection after liver transplantation.Methods The functional efficiency of antibody Fab in blocking hepatitis B reinfection after LT was analysis and studied by vitro infection test,complement toxicity assay and virus infection test,calculated the antibody absorption rate and cell death rate and cell infection rate,Results When the group with and the group without recombinant antibody Fab were compared,the antibody absorption rate,cell death rate and cell infection rate between the 2 groups showed sigificant defference(P