Determination of Two Components in Compound Chlortetracycline Hydrochloride Ointment by Dual Wavelength Spectrophotometry / 中国药房
China Pharmacy
; (12)2001.
Article
in Zh
| WPRIM
| ID: wpr-530289
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:To determine the contents of chlortetracycline hydrochloride and tetracaine hydrochloride in compound chlortetracycline hydrochloride ointment.METHODS:Dual wavelength spectrophotometry was used to determine the two components.The absorbance of the two components was determined at wavelength of 311 nm,368 nm and 387.5 nm,respectively;and the contents of which were computed as well.RESULTS:The linear ranges for chlortetracycline hydrochloride and tetracaine hydrochloride were 9.90~29.71 ?g?mL-1 and 5.99~17.98 ?g?mL-1(r=0.999 9),respectively,with average recovery rates at 99.37%(RSD=0.31%,n=9) and 98.31%(RSD=0.23%,n=9),respectively.CONCLUSION:The method is simple,rapid and accurate,and suitable for the determination of compound chlortetracycline hydrochloride ointment.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2001
Document type:
Article