Retrospective Analysis of ADR Cases in Our Hospital in 2007 / 中国药房

ABSTRACT

OBJECTIVE:To analyze the features and general patterns of adverse drug reactions (ADR) occurred in our hospital. METHODS: 209 ADR case reports collected in our hospital in 2007 were analyzed statistically in respect of patients' age and sex, route of administration, category of the drugs, organs and systems involved, and clinical manifestation of the ADRs. RESULTS: The ADR were more likely caused via intravenous dip (129 cases, 61.72%). Anti-infectives had the highest proportion to induce ADR(94 cases,44.98%), followed by nervous system drugs and cardiovascular system drugs. Quinolones were the leading anti-infective drugs causing ADR(35 cases, 37.23%), of which, Levofloxacin dominated the first place. The main presentation of the ADR was damage of skin and its appendages such as erythra and pruritus etc, followed by the lesions of digestive system and circulatory system. CONCLUSION: ADR monitoring awareness should be strengthened and the related ADR reporting system should be improved.